rapidlasso LAStools Suite 2024 build 10/08

Our LiDAR processing tools are widely known for their blazing speeds and high productivity. Our software combines robust algorithms with efficient I/O and clever memory management to achieve high throughput for data sets containing billions of points.

Our popular LAStools software suite has deep market penetration and is heavily used in the commercial sector, government agencies, research labs, and educational institutions alike — filtering, tiling, rasterizing, triangulating, converting, clipping, quality-checking, etc. TeraBytes of LiDAR every day.

Our open-source LiDAR compressor LASzip has become the de facto industry standard for compressed LiDAR. It has won the 2012 Geospatial World Forum Technology Innovation Award and was voted 2nd place for ”most innovative product” at INTERGEO 2012.

Bentley RAM 2024.1

RAM Connection Standalone 24.00.01.237, RAM Elements 24.00.00.154, RAM Structural System 24.00.01.018

Легко реализовывайте высококачественные и экономичные проекты с использованием различных бетонных, стальных и балочных строительных конструкций. Проектируйте, анализируйте и создавайте документацию по вашим проектам зданий для экономии времени и средств. Максимально повысьте рентабельность ваших инвестиций в ПО благодаря полностью интегрированному набору приложений для комплексного анализа, проектирования и оформления документации для стальных и бетонных конструкций. Повышение вашей производительности за счет устранения утомительных и трудоемких задач с помощью практических приложений RAM. Любые виды проектирования: от отдельных компонентов до крупномасштабного строительства и фундаментов.

RAM Structural System
Надежное оснащение и быстрая разработка высококачественных и экономичных проектов с использованием различных бетонных, стальных и балочных строительных конструкций.

RAM Connection
Анализ, проектирование и мгновенная проверка всех типов соединений с комплексными расчетами и соблюдением сейсмических требований.

RAM Elements
Выполнение анализа и проектирование – включая 3D конечно-элементный анализ – практически любого типа строительной конструкции и структурных компонентов в едином доступном приложении.

Bentley STAAD Pro Advanced 2024 version 24.00.00.577

Bentley STAAD.Pro - лидер в области программного обеспечения для расчета строительных конструкций и проектирования. Bentley STAAD.Pro - выбор профессионала для проектирования любых структур, в том числе водопропускных труб, нефтехимических заводов, тоннелей, мостов, многоквартирных домов и многих других конструкций из стали, бетона, лесоматериалов, алюминия и холодногнутой стали. Bentley STAAD.Pro сертифицирован по системе сертификации ГОСТ Р.

Thunderhead Ventus 2024.1.0702

Ventus is designed to provide a pressurization simulation for smoke control analysis. The simulation is performed by CONTAM, an open-source application maintained and developed by NIST.

Like PyroSim and FDS, Ventus provides a premium user experience for industry leading simulation software. By utilizing our expertise in delivering 3D modeling applications for fire protection eningeering, Ventus will exceed the demands of CONTAM users who want to accelerate their smoke control projects.

1. Ventus allows users to build 3D models of pressure zones based on actual building geometry.
2. Ventus manages multi-variable scenarios for simplified batch CONTAM simulation and analysis.
3. Ventus tabulates results data for multiple scenarios into digestible CSV data and 3D visuals.

Whether for stairwells, atriums, or underground buildings, proper air handling systems must be designed for pressurized smoke control in case of emergency. Ventus provides a clear and efficient path from modeling a building to understanding temperatures, pressures, and densities so that the proper solution can be reached.

Thunderhead Engineering supports you every step of the way. Whether you want in-depth training or self-taught materials, you can learn performance-based design modeling with greater efficiency and proficiency. We design our software for anyone to learn, and our customers are delighted when our support team helps them succeed.

Thunderhead PyroSim 2024.1.0702

PyroSim – это пользовательский интерфейс для программы Fire Dynamics Simulator (FDS). Полевая модель FDS может предсказывать распространение дыма, температуры, угарного газа и других опасных факторов во время пожара. Результаты моделирования используются для обеспечения безопасности зданий при проектировании, определения безопасности существующих зданий, реконструкции пожаров при расследованиях, и помощи в тренировках пожарных. FDS – мощный инструмент для моделирования пожара, разработанный Национальным институтом стандартов и технологий (National Institute of Standards and Technology – NIST). FDS моделирует сценарии пожара с использованием вычислительной гидродинамики (CFD), оптимизированной для низкоскоростных температурно-зависимых потоков. Такой подход оказывается очень гибким, и может быть применен к различным пожарам, начиная от горения в печах и до пожаров на нефтяных танкерах. Также с помощью FDS может быть выполнено моделирование, не включающее горение, например, работа вентиляции в зданиях. Расчетная модель FDS и программа для визуализации Smokeview тесно встроены в PyroSim.

Tutorials

Thunderhead Pathfinder 2024.1.0813

Pathfinder - симулятор эвакуации, использующий современные методы исследований в области информатики для моделирования движения людей, опираясь на технологии, применяемые в игровой и компьютерной графике. Pathfinder предоставляет инструменты, необходимые для проектирования надежных решений относительного расположения зданий и конструктивных систем противопожарной защиты. Несколько режимов моделирования и настраиваемых свойств пассажиров позволит вам с легкостью исследовать различные сценарии, позволяющие выполнить осторожные и оптимистичные оценки ожидаемого времени эвакуации. Pathfinder является агентом-симулятором, т.е. каждый житель использует набор отдельных параметров и принимает решения независимо друг от друга на протяжении всей симуляции. В дополнение к передовому симулятору движения пешеходов, Pathfinder включает в себя интегрированный пользовательский интерфейс и 3D-визуализацию результатов.

Tutorials

BioSolvetIT infiniSee v6.2.0

infiniSee is a virtual screening platform. Based on similarity, it finds molecules of interest in chemical spaces of (almost) infinite size. Given a template or query molecule, infiniSee returns similar molecules from these chemical spaces — or from screening libraries.

With infiniSee you can finally compare apples and oranges. The underlying concept of infiniSee is strikingly easy: Instead of searching already ”assembled” molecules, we instead perform a combinatorial build-up of compounds from ”fragments”. Sources of fragments can be either combinatorial libraries or any fragment-generating procedure. infiniSee opens the possibility to screen billions of compounds through its similarity search technology by navigating vast Chemical Spaces and searching for distant neighbors of a query molecule. Results will be delivered within typically less than a minute on a standard laptop. Optionally, you can define fuzzy pharmacophores to increase the diversity of scaffolds or request important molecular structures to be present in the hits.

The ingenious twist of infiniSee is the possibility of searching not only in colossal Chemical Spaces, but the ability to also comb through spaces of different origins. The number of identical structures in sets from different spaces was found to be extremely low (Lessel et al. 2019) due to the design and setup of the spaces, as well as the diversity of the employed building blocks. No matter how big your in-house library and no matter how many compounds you acquire to add to it, it will only be a tiny fraction of what your chemists are capable of synthesizing. Involving distinct Chemical Spaces increases your chances of finding accessible molecules you would have missed otherwise.

Sometimes the perfect solution is within reach in your own compound library without realization. You can design your own Chemical Space with your accumulated, in-house knowledge and resources. Reactions and building blocks can be defined to create massive numbers of virtual compounds. Multiple big pharma companies built their own, in-house Chemical Spaces to search for scaffold alternatives to reduce costs and time.

BioSolvetIT SeeSAR v13.1.1

SeeSAR fosters innovation during every step of your drug design process. The app includes all tools vital for handling your compounds and target structures which have been fine-tuned to the needs of any chemist. Helpful features such as ADME properties assessment, comprehensive color coding, unoccupied binding pocket visualization, and many others, support you in making sound and interactive decisions. All our tools are based on solid and transparent science cited in over a thousand publications. Follow the button if you want to learn more about the science behind SeeSAR.

Drag and drop your protein, or search comfortably in an online database. Within seconds, your target is prepared and you can get started.

Modify your protein according to your needs. Explore rotamers, introduce mutations, and customize side chains.

SeeSAR automatically detects the binding site of a ligand for you. In addition, you can precisely expand it by adding individual residues — or with a single click to find empty pockets in your protein.

Modify molecules to your taste in 2D or 3D on-the-fly. Once you are done, the molecules are directly prepared for your tasks.

Estimate affinities and interpret the results using the visualized HYDE score. Filter your compounds for relevant parameters, calculate ADME properties, and gain full control over ligand-target interactions.

Ideate without limits! Discover new scaffolds, explore, and grow into free cavities, or link molecules using fragment libraries for elegant solutions.

Dock your compounds with one single click! Screen libraries for actives, and instinctively evaluate your results.

Align your compounds without the need of a target structure based on their molecular similarity.

Change log

ioAnalytics ioGAS v8.2 build 202054

ioGAS is a leading exploratory data analysis software application developed specifically for the resources industry. Traditional methods to analyse results would take many hours and is prone to human error; ioGAS can generate accurate results in a fraction of the time. Over the past decade a wide range of visual analytics and advanced quantitative tools have been developed to help you obtain a greater insight into the underlying structure of your data.

VSN Genstat v24.1.0.242

Genstat is a powerful data analysis software that delivers insights for confident decisions. Its comprehensive suite of statistical tools, including leading ANOVA and REML, ensures trustworthy results even for the most intricate research questions.

Flexible statistical analysis for any field of research! Genstat equips researchers with a powerful toolkit to uncover valuable insights and make informed decisions. From foundational methods like ANOVA and regression to advanced techniques such as mixed models and spatial analysis, Genstat allows you to tackle any analytical challenge with confidence. Whether you’re exploring relationships between variables, generating experimental designs, or performing multivariate analyses, Genstat’s intuitive interface and robust algorithms make it the perfect choice for researchers.

Unlock the true potential of your data with Genstat, a versatile software package designed for education and research. With its flexibility and user-friendly approach, Genstat empowers users across all fields of research to delve into their data with ease and precision.

Navigate the data landscape effortlessly with our comprehensive menus, tailored to guide both technical and non-technical users towards accurate and effective data utilization. But that’s not all - Genstat goes beyond the basics. Our powerful programming language empowers you to craft new techniques and conduct complex experiments.

Dive into a world of expansive possibilities with Genstat’s vast range of data procedures, data management, and dynamic graphical capabilities. Seamlessly store and manipulate your data using our robust spreadsheet facilities. Engage with your plots like never before through our intuitive graphics viewer, allowing you to edit and interact with your visualizations.