About 33C0

For more over 20 years we needed his help. Now he desperately needs ours. Not only help, but support!

I think you know what you have to do.

If you can, please donate a couple of pennies to the following details:

1. PayPal: wilson.bibe@hotmail.com
2. Bank Transfer: Country - Brazil; Account Holder - Wilson Cavallari Bibe Junior; Bank : Nu payments SA; Agency : 0001; Account Number : 89475891-8; Bank Number : 0260

Also, go to your nearest church and say a prayer for his health!!!

Things are bad, but there is ALWAYS hope!!!

Maptek Vulcan 2022.4

Vulcan is the world’s premier 3D mining software solution. Vulcan users can validate and transform raw mining data into dynamic 3D models, accurate mine designs and operating plans. Bundle packages are available for each specific mining scenario and can be customised with different modules for all stages of the mine’s life cycle, creating the total solution for mining companies worldwide.

BioSolvetIT SeeSAR v14.1

SeeSAR fosters innovation during every step of your drug design process. The app includes all tools vital for handling your compounds and target structures which have been fine-tuned to the needs of any chemist. Helpful features such as ADME properties assessment, comprehensive color coding, unoccupied binding pocket visualization, and many others, support you in making sound and interactive decisions. All our tools are based on solid and transparent science cited in over a thousand publications. Follow the button if you want to learn more about the science behind SeeSAR.

Drag and drop your protein, or search comfortably in an online database. Within seconds, your target is prepared and you can get started.

Modify your protein according to your needs. Explore rotamers, introduce mutations, and customize side chains.

SeeSAR automatically detects the binding site of a ligand for you. In addition, you can precisely expand it by adding individual residues — or with a single click to find empty pockets in your protein.

Modify molecules to your taste in 2D or 3D on-the-fly. Once you are done, the molecules are directly prepared for your tasks.

Estimate affinities and interpret the results using the visualized HYDE score. Filter your compounds for relevant parameters, calculate ADME properties, and gain full control over ligand-target interactions.

Ideate without limits! Discover new scaffolds, explore, and grow into free cavities, or link molecules using fragment libraries for elegant solutions.

Dock your compounds with one single click! Screen libraries for actives, and instinctively evaluate your results.

Align your compounds without the need of a target structure based on their molecular similarity.

BioSolvetIT infiniSee v6.2.0

infiniSee is a virtual screening platform. Based on similarity, it finds molecules of interest in chemical spaces of (almost) infinite size. Given a template or query molecule, infiniSee returns similar molecules from these chemical spaces — or from screening libraries.

With infiniSee you can finally compare apples and oranges. The underlying concept of infiniSee is strikingly easy: Instead of searching already ”assembled” molecules, we instead perform a combinatorial build-up of compounds from ”fragments”. Sources of fragments can be either combinatorial libraries or any fragment-generating procedure. infiniSee opens the possibility to screen billions of compounds through its similarity search technology by navigating vast Chemical Spaces and searching for distant neighbors of a query molecule. Results will be delivered within typically less than a minute on a standard laptop. Optionally, you can define fuzzy pharmacophores to increase the diversity of scaffolds or request important molecular structures to be present in the hits.

The ingenious twist of infiniSee is the possibility of searching not only in colossal Chemical Spaces, but the ability to also comb through spaces of different origins. The number of identical structures in sets from different spaces was found to be extremely low (Lessel et al. 2019) due to the design and setup of the spaces, as well as the diversity of the employed building blocks. No matter how big your in-house library and no matter how many compounds you acquire to add to it, it will only be a tiny fraction of what your chemists are capable of synthesizing. Involving distinct Chemical Spaces increases your chances of finding accessible molecules you would have missed otherwise.

Sometimes the perfect solution is within reach in your own compound library without realization. You can design your own Chemical Space with your accumulated, in-house knowledge and resources. Reactions and building blocks can be defined to create massive numbers of virtual compounds. Multiple big pharma companies built their own, in-house Chemical Spaces to search for scaffold alternatives to reduce costs and time.

Schlumberger Waterloo Hydrogeologic Visual MODFLOW Flex v11.0

Visual MODFLOW Flex is the industry standard software for 3D groundwater flow, heat and contaminant transport modeling.

• Integrated Conceptual and Numerical Groundwater Modeling
• Powerful 2D and 3D Visualization Capabilities
• Intuitive and Easy-to-Use

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CYPE Ingenieros CYPE 2026.a Multilingual (online installer)

CYPE programs have a wide range of national and international codes available which are applied to carry out the analysis, design and check of reinforced concrete, rolled steel, welded steel, cold-formed steel, composite, aluminium and timber structures for gravitational, wind, seismic and snow loads.

CYPE's building services programs contain design codes which are used to analyse and design building services (water supply, waste water, air conditioning, solar capture for hot sanitary water, lightning protection, lighting, gas, electricity and telecommunication installations), and to check thermal and acoustic insulation, the building's energy certification and fire safety.

CYPECAD - program that carries out the analysis and design of reinforced concrete and steel structures, subject to horizontal and vertical loads, for homes, buildings and civil work projects. Its use guarantees maximum analysis reliability and optimum drawing design. The geometry of the structure can be introduced automatically. The user can personalise the design and edit the elements that have been introduced, with the on-screen support provided: numerous help options and error and warning texts. Provides very complete and precise construction drawings of the structure. CYPECAD is adapted to the latest national and international construction codes.

CYPE 3D - it is an agile and efficient program brought about to carry out the design of three dimensional structures composed of steel and timber bars, and their foundations, which includes pad footings, pile caps and strap and tie beams. Additionally, these can be redesigned and so obtain their maximum optimisation. It has been adapted to national and international steel, timber, aluminium and concrete construction codes. The program carries out the analysis, design and check of the fire resistance of timber sections. Performs a seismic analysis of the structure (Modal Spectral Analysis) according to national and international codes. Second order effects (P-delta)  are considered with wind and seismic loads.

CYPE-Connect - the program can check slabs with or without transverse punching shear reinforcement, takes into account the presence of openings or lightweight zones in the slab, and the position of the supports (internal, edge or corner). Punching shear verification is a program that checks the Failure Limit State of concrete for punching shear in flat and waffle slabs exposed to concentrated loads from rectangular or circular supports. ]

Вниманию российских проектировщиков: программный комплекс CYPECAD получил сертификат соответствия №0896268 требованиям нормативных документов: 

• СП 20.13330.2011 Нагрузки и воздействия Актуализированная редакция СНиП 2.01.07-85
• СП 63.13330.2012 Бетонные и железобетонные конструкции. Актуализированная редакция СНиП 52-101-2003
• СП 14.13330.2011 Строительство в сейсмических районах. Актуализированная редакция СНиП II-7-81

Cydarex CYDAR Professional 2025 v8.3.2.6

CYDAR software, a product of Cydarex, is a specialized tool for analyzing SCAL data on cores and cuttings in petroleum engineering. This software interprets SCAL (Special Core Analysis) tests on cores and cuttings to examine important parameters such as permeability, capillary pressure, electrical properties, and oil recovery. CYDAR, using the latest methods and techniques, provides high accuracy and efficiency in reservoir simulation and analysis.

CYDAR also includes several modules, each designed for specific analyses, including mercury injection and withdrawal (MICP), absolute and relative permeability calculations, centrifuge tests, and electrical measurements. With a user-friendly interface and comprehensive database, CYDAR provides automated and accurate reporting. In addition, the ability to integrate with other software and provide output in a variety of formats is one of the outstanding features of CYDAR.

 ACI Services eRCM Thermo 2024 v1.10.2.0

Calculating accurate compressor performance requires accurate thermodynamics. eRCM Thermo integrates ProSim’s Simulis Thermodynamics, allowing gas mixture modeling from nearly 400 individual gas components.

Once a gas/gas mixture is entered, eRCM Thermo dynamically calculates: Gas K (via CP/CV), Gas K (via balanced entropy), Compressibility (Z) factors, Specific Gravity and Density, Water Saturation, Hydrocarbon Liquid Dropouts, Phase envelope curves, Water drop out curves, Hydrate formation curves, Gas Mixing (e.g. from a side stream in), Speed of sound through gas, Variety of Units, And more, like Enthalpy and Entropy.

ACI Services eRCM Pro 2025 v1.27.2.0

eRCM Pro replaces the highly successful eRCM Reciprocating Compressor Modeling Software, which enjoyed a twenty-year journey of helping end users model, tune, reapply, and configure their reciprocating compressors.

With so many compressors, so many performance methods, so many PLC implementations and so many restrictions for safe use, ACI’s eRCM Modeling Software provides the ideal solution to model compressor performance.

Simply specify the compressor’s geometry (frame, cylinder, stage, throw, valving, etc.) via direct inputs or by importing data from OEM software, and eRCM Pro displays that unit’s performance curves: Pressure vs. Load, Pressure vs. Flow, Pressure vs. Pressure and more, including graphs of net rod load forces, PV/PT cards, Torque Effort, and more.

Operating conditions change. Will adding a 500 inі clearance pocket to a cylinder’s head end give enough unloading to accommodate the new operating map? Within seconds you’ll have your answer via eRCM Pro.

Tired of Gas Control using one method to predict unit performance, while engineers use another, and the PLC/operators are using yet another method to actually control the hardware? eRCM provides one methodology for disciplines within your company.

Want to see if the packager’s unloading sequence can be improved? With eRCM Pro you can easily check any combination of volume pockets and end deactivation. Including adding spacers to increase fixed clearances or adding filler pieces to volume pockets to decrease additional clearances. You can even check safety at Start Up, and check safety if certain valves fail.

No compressor performance program would be complete without the ability to improve your models. eRCM Pro does just this. Enter valid analyzer data in the tuning section, and eRCM Pro will auto-adapt the performance predictions to accommodate the real-world effects of pulsation, actual valve and parasitic losses, friction losses, etc.

eRCM Pro features:

• Model entire stations
• Manage previous versions of your models
• Fully International aware interface
• Impressive list of Units of Measure
• Advanced thermodynamic calculations using ProSim now included – full support for 400 gases with liquid dropouts
• Still, the fastest performance and graphs in the industry
• As you expect with eRCM, fully dynamic compressor performance, PV cards, Force Plots, Torque Effort Plots, etc.
• Advanced support for Side Streams and Gas Mixing
• Improved valve modeling
• Improved gas preheat modeling
• Improved Load Step Sequence creation
• Full tables, curves, and 3D plot generation
• Support for Clearance devices, End Deactivation devices, Timed-valve Closing devices, Gas Stepless devices, and even variable stroke devices

Schrodinger Suite 2025-2

Schrodinger is a scientific leader in computational chemistry, providing software solutions and services for life sciences and materials research. Schrodinger aims to provide integrated software solutions and services that truly meet its customers' needs. We want to empower researchers around the world to achieve their goals of improving human health and quality of life through advanced computational techniques that transform the way chemists design compounds and materials. By building and deploying breakthrough scientific software solutions and forming collaborations and partnerships, we help scientists accelerate their research and development activities, reduce costs, and make novel discoveries that might otherwise not be possible.

Schrodinger software suite is a drug design software using both ligand and structure-based methods. Schrodinger provides accurate, reliable, and high performance computational technology to solve real-world problems in life science research. It provides superior solutions and services for the design, selection, and optimization of novel drug candidates. Schrodinger's predictive models will enable drug discovery scientists to assess properties of chemical compounds early in the discovery process and to select drug candidates that have optimal profiles. The predictive power of Schrodinger's software allows scientists to accelerate their research and development activities, reduce research costs, and make novel discoveries that might not be possible with other computational or experimental approaches.